PANM 데이터베이스 업데이트 (Version 5.1) : 연체동물 전사체 서열 분석의 정확도 증진을 위한 오염되어진 곰팡이 유전자 서열 검색기능 추가

초록

The PANM database (Protostome DB) is a public repository of protein sequences available from the Protostomia group (includes Arthropoda, Mollusca, and Nematoda). The latest version of PANM DB v5.0 (released in 2022) contained 21,276,123 protein sequences that comprised 4% of the total NCBInr protein data. In this study, an update of PANM DB, i.e., version 5.1, is presented that could accurately analyze the large-scale transcriptome data of molluscs for the contaminating fungal gene sequences. This version can filter out the fungal genes, thereby restricting the annotation to molluscs-only sequences. Using the database, we confirmed 1,589,546 amino acid sequences from 32 fungal species, which can be essentially filtered from the unigenes of 20 species of endangered molluscs. In general, the updated version of PANM DB is expected to enhance the accuracy of bioinformatics analyses of invertebrate NGS data, providing a valuable resource for researchers. PANM version 5.1 can be downloaded for free at https://panm.sch.ac.kr/ for local BLAST analysis.

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