Nutrient Intake and Bone Mineral Density by Nutritional Status in Patients with Inflammatory Bowel Disease

초록

Background: Malnutrition among inflammatory bowel disease (IBD) may arise from fac-tors including inadequate dietary intake, malabsorption, and progression of disease. IBDhas been reported an increased prevalence of low bone mass. The aims of the presentstudy were to evaluate the nutritional status and to investigate the correlation betweenbone mineral density (BMD) and nutrient factors in patients with IBD. Methods: A totalof 41 subjects were classified into normal group (n=21) and malnourished group (n=20) by the subjective global assessment result. We surveyed the dietary habit, nutrientintake, and BMD. Results: Subjects’ average age was 36.7 years old, and included 26 ul-cerative colitis and 15 Crohn’s disease. The serum C-reactive protein (CRP) was signifi-cantly higher and serum calcium was significantly lower in the malnourished group. Lower bone density subjects were more in the malnourished group but no significantdifference. Intake of energy, protein, carbohydrate, fiber, iron, sodium, potassium, zinc,vitamin B6, vitamin C and folate were significantly lower in the malnourished group. TheBMD of malnourished group showed correlation with triceps skin fold thickness (TSF),CRP, dietary calcium, phosphorous, iron, animal iron, zinc and vitamin. Conclusions: Theresults suggested that adequate intake of nutrients is important to prevent bone lossand systemic education programs are need for IBD patients.

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