Do We Perform a Perfect Endoscopic Hemostasis Prophylactically with Argon Plasma Coagulation in Colonic Endoscopic Mucosal Resection?

초록

Submucosal injection for endoscopic mucosal resection (EMR) may effect performing the prophylactic argon plasma coagulation (APC) of non-bleeding visible vessels on ulcer crater. The purpose of this study was to evaluate the clinical features of visible vessels in iatrogenic ulcers over time after prophylactic APC in colonic EMR. This study was designed as a prospective study. Between August and November 2013, a total of 40 patients who were admitted underwent prophylactic APC for non-bleeding visible vessels after colonic EMR. After confirming whether visible vessels were completely coagulated or not, the number of visible vessels in ulcers was counted over a specific time period, e.g. 1, 3, 5, or 7 min. The mean number of visible vessels was significantly higher at 5 min (0.85 +/- A 1.14) after EMR with prophylactic APC compared to 1 and 3 min (1 min: 0.28 +/- A 0.60, P < 0.001; 3 min: 0.65 +/- A 0.87, P = 0.02) and there was no significant difference between 5 and 7 min (P = 0.31). Multivariate analysis showed that the size of the iatrogenic ulcer after EMR was associated with the occurrence of visible vessels (ulcer size > 1 vs. a parts per thousand currency sign0.5 cm: OR 27.32, 95 % CI 2.86-infinity). A 5-min observation of the ulcer may be advantageous for the assessment of visible vessels after performing colonic EMR with prophylactic APC, and large (> 1 cm) iatrogenic ulcers were associated with the occurrence of visible vessels after colonic EMR.

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