Electrochemical oxidative bromolactonization of unsaturated carboxylic acids with sodium bromide: Synthesis of bromomethylated gamma-lactones

Kim, Rabin; Ha, Jeauk; Woo, Jiwon; Kim, Dae Young

doi:10.1016/j.tetlet.2021.153567

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Electrochemical oxidative bromolactonization of unsaturated carboxylic acids with sodium bromide: Synthesis of bromomethylated gamma-lactones

Kim, Rabin;
Ha, Jeauk;
Woo, Jiwon;
Kim, Dae Young

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12

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12

초록

Electrochemical oxidative bromination and cyclization sequences of unsaturated carboxylic acids were developed in this study. This approach is environmentally-friendly, using bromide anion as bromine radical precursor without external oxidizing reagents. The electrochemical protocol offers a facile way to prepare bromomethylated y-lactones derivatives in moderate to high yields. (c) 2021 Elsevier Ltd. All rights reserved.

키워드

Electrochemical reaction; Bromolactonization; y -Lactones; Anodic oxidation; Alkenoic acids; C-H FUNCTIONALIZATION; MIGRATION SEQUENCES; ALKENOIC ACIDS; ELECTROCATALYTIC APPROACH; RING EXPANSION; QUINOXALIN-2(1H)-ONES; CYCLOPENTANONES; HALOCYCLIZATION; HALOGENATION; BROMINATION

제목: Electrochemical oxidative bromolactonization of unsaturated carboxylic acids with sodium bromide: Synthesis of bromomethylated gamma-lactones

저자: Kim, Rabin; Ha, Jeauk; Woo, Jiwon; Kim, Dae Young

DOI: 10.1016/j.tetlet.2021.153567

발행일: 2022-01-05

유형: Article

저널명: Tetrahedron Letters

권: 88

호: 0

페이지: 1 ~ 5

언어: ENG

출판사: Elsevier BV

발행국가: 영국

분량: 5 페이지

ISSN: P 0040-4039