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A self-pressure-driven blood plasma-separation device for point-of-care diagnostics
- Kim, Hanbi;
- Park, Hyeonseek;
- Chung, Doo Ryeon;
- Kim, Taekyung;
- Park, Eunkyoung;
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17초록
We aimed to develop a portable, simple-to-use, and self-pressure-driven blood plasma-separation device that can be combined with rapid diagnostic test kits. This simple, disposable, and electrical equipment-free apparatus has been designed to separate plasma from a few microliters of blood with only hand-powered operation. The refined plasma sample is then delivered to multiple lateral flow assay kits directly connected to the device for the detection of various serological markers. The required time for all steps was just 1 min. We validated the device through multifaceted experiments. The developed multifunctional device enables to perform all blood test steps of diagnostic medical examination at the point-of-care.
키워드
Point-of-care diagnostics; Blood plasma-separation; Rapid diagnostic test kit; Lateral flow assay; Infectious disease; Serology; WHOLE-BLOOD; SERUM-ALBUMIN; EXTRACTION; HEPATITIS
- 제목
- A self-pressure-driven blood plasma-separation device for point-of-care diagnostics
- 저자
- Kim, Hanbi; Park, Hyeonseek; Chung, Doo Ryeon; Kim, Taekyung; Park, Eunkyoung; Kang, Minhee
- 발행일
- 2022-09
- 유형
- Article
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- Talanta
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- 247
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- 0
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