Applications of Functionalized Carbon Nanotubes for the Therapy and Diagnosis of Cancer

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초록

Carbon nanotubes (CNTs) are attractive nanostructures that serve as multifunctional transporters in biomedical applications, especially in the field of cancer therapy and diagnosis. Owing to their easily tunable nature and remarkable properties, numerous functionalizations and treatments of CNTs have been attempted for their utilization as hybrid nano-carriers in the delivery of various anticancer drugs, genes, proteins, and immunotherapeutic molecules. In this review, we discuss the current advances in the applications of CNT-based novel delivery systems with an emphasis on the various functionalizations of CNTs. We also highlight recent findings that demonstrate their important roles in cancer imaging applications, demonstrating their potential as unique agents with high-level ultrasonic emission, strong Raman scattering resonance, and magnetic properties.

키워드

carbon nanotubes (CNTs); cancer; therapy; nano-carriers; functionalization; NEAR-INFRARED WINDOW; IN-VIVO; PLASMID DNA; INTRACELLULAR DELIVERY; GENE-THERAPY; PHOTOACOUSTIC TOMOGRAPHY; ANTITUMOR-ACTIVITY; TARGETED DELIVERY; RAMAN-SCATTERING; CONTRAST AGENT
제목
Applications of Functionalized Carbon Nanotubes for the Therapy and Diagnosis of Cancer
저자
Hwang, Yongsung; Park, Sung-Hoon; Lee, Jin Woo
DOI
10.3390/polym9010013
발행일
2017-01
유형
Review
저널명
Polymers
권
9
호
1