정맥 내 지질 유탁액 치료 후 성공적으로 회복한 초오 중독 1례

A Case of Aconite Poisoning Successfully Recovered after Intravenous Fat Emulsion Therapy

초록

Aconitum is a genus of various species of flowering plants that belongs to the Family Ranunculaceae. Most Aconitum sp. have extremely toxic alkaloid substances such as aconitine, mesaconitine and hypaconitine. Among these substances, aconitine can cause fatal cardiotoxicity by activating sodium channels followed by calcium channels in myocardial cells. Even though there have been various therapeutic plans suggested comprising antidotes based on diverse case reports and studies, there is no confirmatory treatment protocol for aconite poisoning. Here, we report an aconite poisoning patient who had refractory ventricular tachyarrhythmia that did not respond to intravenous amiodarone therapies even though they were sustained for over 2 hours, but showed successful recovery following intravenous fat emulsions (IFE) therapy.

키워드

AconitineAconitumAntidotesIntravenous fat emulsions
제목
정맥 내 지질 유탁액 치료 후 성공적으로 회복한 초오 중독 1례
제목 (타언어)
A Case of Aconite Poisoning Successfully Recovered after Intravenous Fat Emulsion Therapy
저자
신희준임훈
DOI
10.22537/jksct.2016.14.1.60
발행일
2016
저널명
대한임상독성학회지
14
1
페이지
60 ~ 65