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Early Experience of Oncolytic Virus Injection Combined with Sorafenib in a Patient with Advanced Hepatocellular Carcinoma and Portal Vein Thrombosis
Early Experience of Oncolytic Virus Injection Combined with Sorafenib in a Patient with Advanced Hepatocellular Carcinoma and Portal Vein Thrombosis
- Hyun Ho Jo;
- Seong Joon Chun;
- Jeong-Ju Yoo;
- Min Hee Lee;
- Sang Gyune Kim;
- ... Young Seok Kim
초록
JX-594 is a modified oncolytic poxvirus designed to selectively replicate in and destroy cancer cells. In a pilot study, JX-594 injection followed by sorafenib was well-tolerated in three patients and associated with objective tumor responses. In this study, we report a case in which a patient with advanced hepatocellular carcinoma and portal vein thrombosis was treated with a combination of JX-594 and sorafenib.
키워드
Oncolytic virus; JX-594; Sorafenib
- 제목
- Early Experience of Oncolytic Virus Injection Combined with Sorafenib in a Patient with Advanced Hepatocellular Carcinoma and Portal Vein Thrombosis
- 제목 (타언어)
- Early Experience of Oncolytic Virus Injection Combined with Sorafenib in a Patient with Advanced Hepatocellular Carcinoma and Portal Vein Thrombosis
- 저자
- Hyun Ho Jo; Seong Joon Chun; Jeong-Ju Yoo; Min Hee Lee; Sang Gyune Kim; Young Seok Kim
- 발행일
- 2020
- 저널명
- 대한간암학회지
- 권
- 20
- 호
- 2
- 페이지
- 177 ~ 182