Adenoid cystic carcinoma of the breast: Report of two cases with immunohistochemical profile of C-kit and MYB overexpression

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초록

Adenoid cystic carcinoma (ACC) is a rare tumor with characteristic histologic features. Staining with basal markers for estrogen receptor, progesterone receptor, and HER2 usually shows negative results. Immunohistochemical analysis of C-kit and MYB overexpression of the ACC also has been reported. We report two cases of ACC of the breast with C-kit and MYB overexpression that clinically confirm these previously reported characteristics and suggest that further molecular study of the expression of these two proteins can lead to future therapeutic strategies.

키워드

Adenoid cystic carcinomabreastC-kitMYBimmunohistochemistryEXPRESSIONHEADNECKRARE
제목
Adenoid cystic carcinoma of the breast: Report of two cases with immunohistochemical profile of C-kit and MYB overexpression
저자
Chin, SusieKim, Zisun
DOI
10.4103/0377-4929.142693
발행일
2014-10
유형
Article
저널명
Indian Journal of Pathology and Microbiology
57
4
페이지
611 ~ 613