The diverse biological functions of glutathione S-transferase omega in Drosophila

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11
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12

초록

Glutathione S-transferase omega (GSTO) genes in eukaryotic organisms encode proteins that are important for cell defense. However, the physiological roles of GSTOs have not been fully elucidated yet. Recently, genetic and molecular studies with Drosophila demonstrated that CG6781 is the structural gene of the eye color mutant sepia and that CG6673 is a novel genetic suppressor of the parkin mutant. These results provide valuable insight into the diverse functions of GSTOs in vivo. In this review, we briefly introduce recent studies and summarize the novel biological functions of GSTOs in Drosophila

키워드

ascorbic acid; dehydroascorbate; Drosophila; drosopterin; eye pigments; F1F0-ATP synthase; glutathione S-transferase omega; pyrimidodiazepine; DEPENDENT DEHYDROASCORBATE REDUCTASE; AGE-AT-ONSET; THIOREDOXIN REDUCTASE; GENE; IDENTIFICATION; PURIFICATION; MELANOGASTER; POLYMORPHISM; RESISTANCE; STRESS
제목
The diverse biological functions of glutathione S-transferase omega in Drosophila
저자
Kim, Kiyoung; Yim, Jeongbin
DOI
10.1515/pterid-2013-0017
발행일
2013-06
유형
Review
저널명
Pteridines
권
24
호
1
페이지
117 ~ 120