Current preparedness and future directions of Korean cytogenetic biodosimetry laboratories for managing large-scale radiological incidents in South Korea

  • Lee, Jong Yun
  • Lee, Yang Hee
  • Yang, Su San
  • Lee, Ye Eun
  • Hong, Eun-Hee
  • ... Lee, Younghyun
  • 외 5명
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초록

The current activities of the Korean Biological Dosimetry Network (K-BioDos) have focused on harmonizing the scoring of chromosomal aberrations. However, other biodosimetry procedures have not been sufficiently considered in preparation for large-scale radiological accidents. This study aimed to investigate the current status of various resources for performing cytogenetic biodosimetry on many samples and explore the limitations and future directions for analyzing large sample sizes. Although the capacity to score cytogenetic aberrations has improved, processing thousands of samples within a limited period remains a significant challenge. To further enhance biodosimetry performance, we recommend the establishment of automated systems for sample handling and increased government support to ensure adequate material resources. Additionally, we highlight the importance of developing strategies to assess occupationally exposed populations. These measures could enable K-BioDos and other national and international networks to establish comprehensive frameworks for dose assessment in large-scale radiological incidents.

키워드

CHROMOSOME TRANSLOCATIONSRADIATION BIODOSIMETRYDICENTRIC CHROMOSOMESBIOLOGICAL DOSIMETRYIONIZING-RADIATIONDOSE-RESPONSEACCIDENTEXPOSURENETWORKNEEDS
제목
Current preparedness and future directions of Korean cytogenetic biodosimetry laboratories for managing large-scale radiological incidents in South Korea
저자
Lee, Jong YunLee, Yang HeeYang, Su SanLee, Ye EunHong, Eun-HeeLee, In-KyungOh, Su JungJeong, Soo KyungBack, SengminCho, MinsuLee, Younghyun
DOI
10.1093/rpd/ncaf113
발행일
2025-11
유형
Article
저널명
Radiation Protection Dosimetry
201
19
페이지
1233 ~ 1241