Interplay between Intestinal Microbiota and Host Immune System

Interplay between Intestinal Microbiota and Host Immune System

초록

Whether we are aware or not, diverse microorganisms are living on almost all environmentally exposed surfaces on our body without eliciting harmful immune responses. In fact, recent understanding from numerous studies indicates that our health is highly dependent on the contribution of intestinal commensal bacteria. It appears through its symbiotic interaction with the host, which is the result of millions of years of co-evolution, the microbiota shapes the immune system. In this review, we discuss the relationship between host physiology and commensal bacteria and explore the molecular mechanisms by which the adaptive immune system is influenced by the intestinal microbiota.

키워드

Intestinal microbiota; Dysbiosis; Adaptive immune system; CD4+ T cells
제목
Interplay between Intestinal Microbiota and Host Immune System
제목 (타언어)
Interplay between Intestinal Microbiota and Host Immune System
저자
Sarkis K. Mazmanian; 이윤경
DOI
10.4167/jbv.2014.44.1.1
발행일
2014
저널명
Journal of Bacteriology and Virology
권
44
호
1
페이지
1 ~ 9