티록신 결합 글로불린 결핍을 동반한 저티록시혈증 1예

A Case of Hypothyroxinemia with Thyroxine-Binding-Globulin Deficiency
  • 허순미; 
  • 김신희; 
  • 변동원; 
  • 서교일; 
  • 유명희; 
  • ... 박형규

초록

The transport proteins such as thyroxine-binding-globulin (TBG), albumin and transthyretin carry over 99% of circulating thyroid hormones. TBG is a major thyroid hormone transport protein in serum. Although TBG deficiency does not have metabolic consequences,it has diagnostic implications as it can lead to an incorrect interpretation of thyroid function tests. We experienced a case that a man who had an abnormal thyroid function showed unexpectedly low concentrations of serum total thyroxine. We detected the low TBG in his serum and he was diagnosed the TBG deficiency. We report this case along with a review of the related literature.

키워드

Thyroxine-binding-globulin deficiency; Hypothyroxinemia
제목
티록신 결합 글로불린 결핍을 동반한 저티록시혈증 1예
제목 (타언어)
A Case of Hypothyroxinemia with Thyroxine-Binding-Globulin Deficiency
저자
허순미; 김신희; 변동원; 서교일; 유명희; 박형규
발행일
2011
저널명
Soonchunhyang Medical Science
권
17
호
2
페이지
161 ~ 163