Initial experiences and usefulness of porcine acellular dermal matrix-assisted prepectoral breast implant surgery: a case series and systematic review

초록

Background We report our experiences with prepectoral placement breast implant sur gery using Supporix (HansBioMed), a porcine acellular dermal matrix (PADM), for cos metic and reconstructive indications. The clinical efficiency, safety, and cost-effective ness of PADM were also discussed. Methods A single-center, retrospective study was designed from December 2017 to De cember 2019. The participants were Korean women who underwent PADM-assisted prepectoral breast implant surgery performed by two surgeons. All complications were registered and analyzed. A systematic review and meta-analysis of complication rates af ter PADM-assisted prepectoral breast implant surgery were conducted for comparison with other studies. A subgroup analysis was performed according to the operation type: the cosmetic breast surgery (CBS) group, the immediate implant-based breast recon struction (IIBR) group, and the delayed implant-based breast reconstruction (DIBR) group. Results Twenty breasts in 16 patients were included in our study (median follow-up pe riod, 8.25 months). In a systematic review, 20 publications with a total of 2,504 breasts in 1,921 women were quantitively analyzed. The overall complication rates in our study and other studies were 14% and 24% in the total group analysis, 0% and 12% in the CBS group, 62% and 26% in the IIBR group, and 0% and 28% in the DIBR group, respectively. Conclusions Our data support the effectiveness of PADM-assisted prepectoral breast implant surgery, which was comparable to other studies. PADM was effective for re ducing seroma and hematoma in the revision CBS group and the DIBR group. In the IIBR group, it was helpful in preventing implant loss and explantation.

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