Different Responses to Clarithromycin in Patients with Cryptogenic Organizing Pneumonia

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2

초록

Cryptogenic organizing pneumonia (COP) is an idiopathic interstitial pneumonia characterized by a subacute course and favorable prognosis with corticosteroids. However, some patients show resistance to steroids. Macrolides have been used with success in those patients showing resistance to steroids. A few reports showed treatment failure with macrolides in patients with COP who were resistant to steroids. In this report, we described two cases of COP who showed different responses to clarithromycin. One recovered completely, but the other gradually showed lung fibrosis with clarithromycin.

키워드

Cryptogenic Organizing Pneumonia; Clarithromycin; Macrolides; Adrenal Cortex Hormones
제목
Different Responses to Clarithromycin in Patients with Cryptogenic Organizing Pneumonia
저자
Oh, Ji Hyun; Oh, Dong Jun; Koo, So-My; Kim, Yang Ki; Kim, Ki Up; Kim, Hyun Jo; Kim, Dong Won; Uh, Soo-Taek
DOI
10.4046/trd.2015.78.4.401
발행일
2015-10
유형
Article
저널명
Tuberculosis and Respiratory Diseases
권
78
호
4
페이지
401 ~ 407