Effectiveness and Safety of Bictegravir/ Emtricitabine/Tenofovir Alafenamide in People with HIV in Korea: 24-Month Data from BICSTaR

  • Kim, Yeon-Sook
  • Choi, Jun Yong
  • Park, Dae Won
  • Kim, Shin-Woo
  • Kim, Tae Hyong
  • 외 5명
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초록

BICtegravir Single Tablet Regimen is a multi-national observational cohort study evaluating the effectiveness and safety of bictegravir/emtricitabine/tenofovir alafenamide (BIC/FTC/TAF) in people with human immunodeficiency virus. We present 24-month data from participants in Korea. Eighty-eight participants (36 treatment-naive [TN], 52 treatment-experienced [TE]) were included. At 24 months, 100% (29/29) of TN and 100% (37/37) of TE participants had HIV-1 RNA <50 copies/mL (missing=excluded analysis). BIC/FTC/TAF persistence was 100% (33/33) and 96.1% (49/51) in TN and TE participants, respectively. Drug-related adverse events occurred in 2 TN participants. Improvements in some patient-reported outcomes were observed. BIC/FTC/TAF maintained effectiveness,

키워드

Combination antiretroviral therapyKoreaAsiabictegravirobservational studyANTIRETROVIRAL THERAPYTENOFOVIR ALAFENAMIDEMULTICENTERPHASE-3
제목
Effectiveness and Safety of Bictegravir/ Emtricitabine/Tenofovir Alafenamide in People with HIV in Korea: 24-Month Data from BICSTaR
저자
Kim, Yeon-SookChoi, Jun YongPark, Dae WonKim, Shin-WooKim, Tae HyongRyu, JulieHarrison, RebeccaLee, Jeong-aPark, FloraLee, Sun Hee
DOI
10.3947/ic.2025.0061
발행일
2025-09
유형
Article
저널명
Infection and Chemotherapy
57
3
페이지
424 ~ 430