Procalcitonin as a Diagnostic Marker for Osteomyelitis in Patients with Pressure Injuries: A Retrospective Study

초록

OBJECTIVETo assess the diagnostic potential of procalcitonin in identifying osteomyelitis in patients with pressure injuries (PIs). METHODSThe authors conducted a retrospective study of 21 patients with PIs from 2017 to 2022. Inflammatory markers (white blood cell count, erythrocyte sedimentation rate, C-reactive protein, procalcitonin) and radiologic images were analyzed to determine osteomyelitis presence. Patients were divided into osteomyelitis-positive and osteomyelitis-negative groups, with marker levels compared statistically. RESULTSBoth C-reactive protein and procacitonin levels were significantly higher in the osteomyelitis group (Ps = .05). Elevated procalcitonin (>0.5) indicated a 10.67 times higher likelihood of osteomyelitis. CONCLUSIONSProcalcitonin may serve as a valuable marker for diagnosing osteomyelitis in patients with PIs, aiding in early detection and treatment planning. Further research with larger cohorts is needed to confirm its diagnostic and monitoring potential.

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