Hard tissue regeneration using bone substitutes: an update on innovations in materials

Citations

WEB OF SCIENCE

67
Citations

SCOPUS

77

초록

Bone is a unique organ composed of mineralized hard tissue, unlike any other body part. The unique manner in which bone can constantly undergo self-remodeling has created interesting clinical approaches to the healing of damaged bone. Healing of large bone defects is achieved using implant materials that gradually integrate with the body after healing is completed. Such strategies require a multidisciplinary approach by material scientists, biological scientists, and clinicians. Development of materials for bone healing and exploration of the interactions thereof with the body are active research areas. In this review, we explore ongoing developments in the creation of materials for regenerating hard tissues.

키워드

Bone substitutes; Bone tissue engineering; Bioceramics; Hydrogel; Biopolymers; GROWTH-FACTOR DELIVERY; BIOACTIVE GLASS; IN-VITRO; CALCIUM-PHOSPHATE; MECHANICAL-PROPERTIES; COMPOSITE SCAFFOLDS; HYDROXYAPATITE COATINGS; FIBROUS SCAFFOLD; CELL THERAPY; STEM-CELLS
제목
Hard tissue regeneration using bone substitutes: an update on innovations in materials
저자
Sarkar, Swapan Kumar; Lee, Byong Taek
DOI
10.3904/kjim.2015.30.3.279
발행일
2015-05
유형
Review
저널명
The Korean Journal of Internal Medicine
권
30
호
3
페이지
279 ~ 293